TVGuide.com offers readers to vote for the Sexiest Stars of 2008, having 'Sam' and 'Dean' up against The Walkers (Brothers & Sisters), Robert and Jason McAllister (Brothers & Sisters), Juliet and Jeremy Darling (Dirty Sexy Money), Nathan and Lucas Scott (One Tree Hill) and Michael Scofield and Lincoln Burrows (Prison Break) on the Sexiest Siblings category.
Click here to vote.