Spoilers from Ask Ausiello

Question: Is Supernatural planning any meta episodes this season? The season has been pretty dark so far. I need a pick-me-up. —Patty
Ausiello: I have a hunch the Nov. 18 episode, titled “Season 7, Time For a Wedding,” should quench your meta/humor thirst. (And before you ask, yes, one of the brothers is the groom.)

Question: Will Sam’s hallucinations and troubles with the collapsed wall in his head be a season-long journey on Supernatural? —Mark
Ausiello: “We don’t really plan for that to ever fully go away,” responds exec producer Sera Gamble. “In terms of that being a condition that Sam has, it’s just part of him now. By the end of last week’s episode, he had started to develop ways of coping with it. And the next step in that story is seeing how his attitude changes and how Dean is dealing with it and his worries about it. But what happened to Sam’s head is pretty permanent.”

Source:  AskAusiello