Dean (Jensen Ackles) and Bobby (Jim Beaver) lock Sam (Jared Padalecki) in Bobby’s panic room so he can detox from the demon blood.
However, as Bobby sees more seals are being broken he tells Dean they should let Sam out to help them fight the impending apocalypse. Dean disagrees and goes to Castiel (Misha Collins) for help.
Sam and Dean have a big blowout confrontation.
Robert Singer directed the episode written by Sera Gamble.