Due to BuddyTV users demanded, the site posted a follow-up to it's first round of the 50 Sexiest Men on TV:
#37 Misha Collins, Supernatural
It’s only appropriate that Misha Collins plays an angel on TV, because the things we’d like to do with him are downright Biblical. His strict demeanor and ever-prominent trench coat try to hide his sexiness, but we still remember him as the hot terrorist who seduced a member of Senator Palmer’s staff back in the first season of 24, so we know exactly how sexy he really is.
#25 Jeffrey Dean Morgan, Grey’s Anatomy
Jeffrey Dean Morgan is so hot that he transcends death. For real, if you are looking for someone to play the world's hottest dead guy on your TV show, JDM seems to be the choice du jour. He plays Izzie's ghost lover on Grey's Anatomy, the beloved departed husband on Weeds, and devoted dead father of the Winchester brothers on Supernatural. While some people think it's strange Izzie Stevens is having ghost sex with Denny, we think you can hardly blame the girl–a man this hot shouldn't be kept from some loving by a little thing like mortality.
Source: Supernatural.tv.