Misha Collins is mentioned on ChicagoNow "Chicagoans on Demand: Windy City stars take over TV":
"Factor in non-Chicago natives who went to school or worked here–Misha Collins, Tina Fey and Amy Poehler, for example–and prime-time TV is bursting with Windy City ties."
According to Wikipedia, Collins studied Social Theory at University of Chicago.
Source: ChicagoNow, Wikipedia.