Sam (Jared Padalecki) and Dean (Jensen Ackles) investigate a small town where people are cheating death. They discover the Reapers have gone missing so they turn to Pamela (guest star Traci Dinwiddie) for help.
She sends them into the spiritual world to find answers and they come face to face with Alastair (guest star Christopher Heyerdahl), who has been kidnapping all the Reapers in order to break another seal.
James Conway directed the episode written by Jeremy Carver.